Combining selective inhibitors of nuclear export (SINEs) with chimeric antigen receptor (CAR) T cells for CD19-positive malignancies

Chimeric antigen receptor (CAR) T cells directed against CD19 (CD19.CAR T cells) have yielded impressive clinical responses in the treatment of patients with lymphoid malignancies. However, resistance and/or relapse can limit treatment outcome. Risk of tumor escape can be reduced by combining treatm...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Wang, Sanmei, Sellner, Leopold, Wang, Lei, Sauer, Tim, Neuber, Brigitte, Gong, Wenjie, Stock, Sophia, Ni, Ming, Yao, Hao, Kleist, Christian, Schmitt, Anita, Müller-Tidow, Carsten, Schmitt, Michael, Schubert, Maria-Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8250584/
https://ncbi.nlm.nih.gov/pubmed/34165175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2021.8121
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