Combining selective inhibitors of nuclear export (SINEs) with chimeric antigen receptor (CAR) T cells for CD19-positive malignancies

Chimeric antigen receptor (CAR) T cells directed against CD19 (CD19.CAR T cells) have yielded impressive clinical responses in the treatment of patients with lymphoid malignancies. However, resistance and/or relapse can limit treatment outcome. Risk of tumor escape can be reduced by combining treatm...

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Bibliografiske detaljer
Udgivet i:Oncol Rep
Main Authors: Wang, Sanmei, Sellner, Leopold, Wang, Lei, Sauer, Tim, Neuber, Brigitte, Gong, Wenjie, Stock, Sophia, Ni, Ming, Yao, Hao, Kleist, Christian, Schmitt, Anita, Müller-Tidow, Carsten, Schmitt, Michael, Schubert, Maria-Luisa
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2021
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8250584/
https://ncbi.nlm.nih.gov/pubmed/34165175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2021.8121
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