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Captopril treatment during development alleviates mechanically induced aortic remodeling in newborn elastin knockout mice

Deposition of elastin and collagen in the aorta correlate with increases in blood pressure and flow during development, suggesting that the aorta adjusts its mechanical properties in response to hemodynamic stresses. Elastin knockout (Eln(−/−)) mice have high blood pressure, pathological remodeling...

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Bibliografske podrobnosti
izdano v:Biomech Model Mechanobiol
Main Authors: Kim, Jungsil, Cocciolone, Austin J., Staiculescu, Marius C., Mecham, Robert P., Wagenseil, Jessica E.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940555/
https://ncbi.nlm.nih.gov/pubmed/31270728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-019-01198-2
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