Elastin haploinsufficiency in mice has divergent effects on arterial remodeling with aging depending on sex

Elastin is a primary structural protein in the arterial wall that contributes to vascular mechanical properties and degrades with aging. Aging is associated with arterial stiffening and an increase in blood pressure. There is evidence that arterial aging follows different timelines with sex. Our obj...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Hawes, Jie Z., Cocciolone, Austin J., Cui, Amy H., Griffin, Diana B., Staiculescu, Marius Catalin, Mecham, Robert P., Wagenseil, Jessica E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792709/
https://ncbi.nlm.nih.gov/pubmed/33035438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00517.2020
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