Elastin haploinsufficiency in mice has divergent effects on arterial remodeling with aging depending on sex

Elastin is a primary structural protein in the arterial wall that contributes to vascular mechanical properties and degrades with aging. Aging is associated with arterial stiffening and an increase in blood pressure. There is evidence that arterial aging follows different timelines with sex. Our obj...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Hawes, Jie Z., Cocciolone, Austin J., Cui, Amy H., Griffin, Diana B., Staiculescu, Marius Catalin, Mecham, Robert P., Wagenseil, Jessica E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792709/
https://ncbi.nlm.nih.gov/pubmed/33035438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00517.2020
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