Elastin haploinsufficiency in mice has divergent effects on arterial remodeling with aging depending on sex

Elastin is a primary structural protein in the arterial wall that contributes to vascular mechanical properties and degrades with aging. Aging is associated with arterial stiffening and an increase in blood pressure. There is evidence that arterial aging follows different timelines with sex. Our obj...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Hawes, Jie Z., Cocciolone, Austin J., Cui, Amy H., Griffin, Diana B., Staiculescu, Marius Catalin, Mecham, Robert P., Wagenseil, Jessica E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792709/
https://ncbi.nlm.nih.gov/pubmed/33035438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00517.2020
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