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Captopril treatment during development alleviates mechanically induced aortic remodeling in newborn elastin knockout mice

Deposition of elastin and collagen in the aorta correlate with increases in blood pressure and flow during development, suggesting that the aorta adjusts its mechanical properties in response to hemodynamic stresses. Elastin knockout (Eln(−/−)) mice have high blood pressure, pathological remodeling...

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書誌詳細
出版年:Biomech Model Mechanobiol
主要な著者: Kim, Jungsil, Cocciolone, Austin J., Staiculescu, Marius C., Mecham, Robert P., Wagenseil, Jessica E.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940555/
https://ncbi.nlm.nih.gov/pubmed/31270728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-019-01198-2
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