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Captopril treatment during development alleviates mechanically induced aortic remodeling in newborn elastin knockout mice

Deposition of elastin and collagen in the aorta correlate with increases in blood pressure and flow during development, suggesting that the aorta adjusts its mechanical properties in response to hemodynamic stresses. Elastin knockout (Eln(−/−)) mice have high blood pressure, pathological remodeling...

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Detalhes bibliográficos
Publicado no:Biomech Model Mechanobiol
Main Authors: Kim, Jungsil, Cocciolone, Austin J., Staiculescu, Marius C., Mecham, Robert P., Wagenseil, Jessica E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940555/
https://ncbi.nlm.nih.gov/pubmed/31270728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-019-01198-2
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