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Captopril treatment during development alleviates mechanically induced aortic remodeling in newborn elastin knockout mice

Deposition of elastin and collagen in the aorta correlate with increases in blood pressure and flow during development, suggesting that the aorta adjusts its mechanical properties in response to hemodynamic stresses. Elastin knockout (Eln(−/−)) mice have high blood pressure, pathological remodeling...

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Dades bibliogràfiques
Publicat a:Biomech Model Mechanobiol
Autors principals: Kim, Jungsil, Cocciolone, Austin J., Staiculescu, Marius C., Mecham, Robert P., Wagenseil, Jessica E.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940555/
https://ncbi.nlm.nih.gov/pubmed/31270728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-019-01198-2
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