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Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis
The p53 gene is an important tumour suppressor gene. Mutant p53 genes account for about half of all lung cancer cases. There is increasing evidence for the anti-tumour effects of statins via inhibition of the mevalonate pathway. We retrospectively investigated the correlation between statin use and...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6938497/ https://ncbi.nlm.nih.gov/pubmed/31892709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56532-6 |
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