Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells

In the present study, we explore the role of apoptosis signal-regulating kinase 1 (ASK1) in denbinobin-induced apoptosis in human lung adenocarcinoma (A549) cells. Denbinobin-induced cell apoptosis was attenuated by an ASK1 dominant-negative mutant (ASK1DN), two antioxidants (N-acetyl-L-cysteine (NA...

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Hlavní autoři: Kuo, Chen-Tzu, Chen, Bing-Chang, Yu, Chung-Chi, Weng, Chih-Ming, Hsu, Ming-Jen, Chen, Chien-Chih, Chen, Mei-Chieh, Teng, Che-Ming, Pan, Shiow-Lin, Bien, Mauo-Ying, Shih, Chung-Hung, Lin, Chien-Huang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686692/
https://ncbi.nlm.nih.gov/pubmed/19405983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-43
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