Activation of a nuclear factor of activated T-lymphocyte-3 (NFAT3) by oxidative stress in carboplatin-mediated renal apoptosis

BACKGROUND AND PURPOSE: Although carboplatin is currently used as a therapeutic drug for ovarian, breast, and non-small cell lung cancers, it has serious side effects including renal and cardiac toxicity. Herein, we examined the effect of carboplatin on murine renal tubular cell (RTC) apoptosis both...

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Detalhes bibliográficos
Main Authors: Lin, Heng, Sue, Yuh-Mou, Chou, Ying, Cheng, Ching-Feng, Chang, Chih-Cheng, Li, Hsiao-Fen, Chen, Chien-Chang, Juan, Shu-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010574/
https://ncbi.nlm.nih.gov/pubmed/20718735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00989.x
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