Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter

E26 transformation-specific sequence 1 (Ets-1), the prototype of the ETS family of transcription factors, is critical for the expression of IL-2 by murine Th cells; however, its mechanism of action is still unclear. Here we show that Ets-1 is also essential for optimal production of IL-2 by primary...

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Hlavní autoři: Tsao, Hsiao-Wei, Tai, Tzong-Shyuan, Tseng, William, Chang, Hui-Hsin, Grenningloh, Roland, Miaw, Shi-Chuen, Ho, I-Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785780/
https://ncbi.nlm.nih.gov/pubmed/24019486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304343110
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