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Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter
E26 transformation-specific sequence 1 (Ets-1), the prototype of the ETS family of transcription factors, is critical for the expression of IL-2 by murine Th cells; however, its mechanism of action is still unclear. Here we show that Ets-1 is also essential for optimal production of IL-2 by primary...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785780/ https://ncbi.nlm.nih.gov/pubmed/24019486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304343110 |
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