Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation

Cerebral cavernous malformation (CCM) is a genetic, cerebrovascular disease. Familial CCM is caused by genetic mutations in KRIT1, CCM2 or PDCD10. Notably, disease onset is earlier and more severe in individuals with PDCD10 mutations. Recent studies have shown that lesions arise from excess Mitogen-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Tang, Alan T., Sullivan, Katie R., Hong, Courtney C., Goddard, Lauren M., Mahadevan, Aparna, Ren, Aileen, Pardo, Heidy, Peiper, Amy, Griffin, Erin, Tanes, Ceylan, Mattei, Lisa M., Yang, Jisheng, Li, Li, Mericko-Ishizuka, Patricia, Shen, Le, Hobson, Nicholas, Girard, Romuald, Lightle, Rhonda, Moore, Thomas, Shenkar, Robert, Polster, Sean P., Roedel, Claudia J., Li, Ning, Zhu, Qin, Whitehead, Kevin J., Zheng, Xiangjian, Akers, Amy, Morrison, Leslie, Kim, Helen, Bittinger, Kyle, Lengner, Christopher J., Schwaninger, Markus, Velcich, Anna, Augenlicht, Leonard, Abdelilah-Seyfried, Salim, Min, Wang, Marchuk, Douglas A., Awad, Issam A., Kahn, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937779/
https://ncbi.nlm.nih.gov/pubmed/31776290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaw3521
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados