Epigenetic reprogramming underlies efficacy of DNA demethylation therapy in osteosarcomas

Osteosarcoma (OS) patients with metastasis or recurrent tumors still suffer from poor prognosis. Studies have indicated the efficacy of DNA demethylation therapy for OS, but the underlying mechanism is still unclear. Here, we aimed to clarify the mechanism of how epigenetic therapy has therapeutic e...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Asano, Naofumi, Takeshima, Hideyuki, Yamashita, Satoshi, Takamatsu, Hironori, Hattori, Naoko, Kubo, Takashi, Yoshida, Akihiko, Kobayashi, Eisuke, Nakayama, Robert, Matsumoto, Morio, Nakamura, Masaya, Ichikawa, Hitoshi, Kawai, Akira, Kondo, Tadashi, Ushijima, Toshikazu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937291/
https://ncbi.nlm.nih.gov/pubmed/31889115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56883-0
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