Epigenetic reprogramming underlies efficacy of DNA demethylation therapy in osteosarcomas

Osteosarcoma (OS) patients with metastasis or recurrent tumors still suffer from poor prognosis. Studies have indicated the efficacy of DNA demethylation therapy for OS, but the underlying mechanism is still unclear. Here, we aimed to clarify the mechanism of how epigenetic therapy has therapeutic e...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Asano, Naofumi, Takeshima, Hideyuki, Yamashita, Satoshi, Takamatsu, Hironori, Hattori, Naoko, Kubo, Takashi, Yoshida, Akihiko, Kobayashi, Eisuke, Nakayama, Robert, Matsumoto, Morio, Nakamura, Masaya, Ichikawa, Hitoshi, Kawai, Akira, Kondo, Tadashi, Ushijima, Toshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937291/
https://ncbi.nlm.nih.gov/pubmed/31889115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56883-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados