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Accumulation of genetic and epigenetic alterations in normal cells and cancer risk

Cancers develop due to the accumulation of genetic and epigenetic alterations. Genetic alterations are induced by aging, mutagenic chemicals, ultraviolet light, and other factors; whereas, epigenetic alterations are mainly by aging and chronic inflammation. The accumulation and patterns of alteratio...

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Bibliografiska uppgifter
I publikationen:NPJ Precis Oncol
Huvudupphovsmän: Takeshima, Hideyuki, Ushijima, Toshikazu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403339/
https://ncbi.nlm.nih.gov/pubmed/30854468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-019-0079-0
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