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Accumulation of genetic and epigenetic alterations in normal cells and cancer risk

Cancers develop due to the accumulation of genetic and epigenetic alterations. Genetic alterations are induced by aging, mutagenic chemicals, ultraviolet light, and other factors; whereas, epigenetic alterations are mainly by aging and chronic inflammation. The accumulation and patterns of alteratio...

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Detalhes bibliográficos
Publicado no:NPJ Precis Oncol
Main Authors: Takeshima, Hideyuki, Ushijima, Toshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403339/
https://ncbi.nlm.nih.gov/pubmed/30854468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-019-0079-0
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