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Accumulation of genetic and epigenetic alterations in normal cells and cancer risk

Cancers develop due to the accumulation of genetic and epigenetic alterations. Genetic alterations are induced by aging, mutagenic chemicals, ultraviolet light, and other factors; whereas, epigenetic alterations are mainly by aging and chronic inflammation. The accumulation and patterns of alteratio...

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Bibliografiske detaljer
Udgivet i:NPJ Precis Oncol
Main Authors: Takeshima, Hideyuki, Ushijima, Toshikazu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403339/
https://ncbi.nlm.nih.gov/pubmed/30854468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-019-0079-0
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