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Accumulation of genetic and epigenetic alterations in normal cells and cancer risk

Cancers develop due to the accumulation of genetic and epigenetic alterations. Genetic alterations are induced by aging, mutagenic chemicals, ultraviolet light, and other factors; whereas, epigenetic alterations are mainly by aging and chronic inflammation. The accumulation and patterns of alteratio...

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Bibliografische gegevens
Gepubliceerd in:NPJ Precis Oncol
Hoofdauteurs: Takeshima, Hideyuki, Ushijima, Toshikazu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403339/
https://ncbi.nlm.nih.gov/pubmed/30854468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-019-0079-0
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