Inflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation

RNF183 is a ubiquitin ligase containing RING-finger and transmembrane domains, and its expression levels are increased in patients with inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, and in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice. Here, we furthe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Yan, Kimura, Yuka, Okamoto, Takumi, Matsuhisa, Koji, Asada, Rie, Saito, Atsushi, Sakaue, Fumika, Imaizumi, Kazunori, Kaneko, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937276/
https://ncbi.nlm.nih.gov/pubmed/31889078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56748-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados