IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes

The unfolded protein response (UPR) not only resolves endoplasmic reticulum (ER) stress, but also regulates cellular physiological functions. In this study, we first linked the UPR to the physiological roles of brown adipose tissue (BAT). BAT is one of the tissues that control energy homeostasis in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Asada, Rie, Kanemoto, Soshi, Matsuhisa, Koji, Hino, Kenta, Cui, Min, Cui, Xiang, Kaneko, Masayuki, Imaizumi, Kazunori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644985/
https://ncbi.nlm.nih.gov/pubmed/26568450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16580
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