IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes

The unfolded protein response (UPR) not only resolves endoplasmic reticulum (ER) stress, but also regulates cellular physiological functions. In this study, we first linked the UPR to the physiological roles of brown adipose tissue (BAT). BAT is one of the tissues that control energy homeostasis in...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Asada, Rie, Kanemoto, Soshi, Matsuhisa, Koji, Hino, Kenta, Cui, Min, Cui, Xiang, Kaneko, Masayuki, Imaizumi, Kazunori
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644985/
https://ncbi.nlm.nih.gov/pubmed/26568450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16580
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