Neutralization of IL-1α ameliorates Crohn’s disease-like ileitis by functional alterations of the gut microbiome

Crohn’s disease and ulcerative colitis are chronic and progressive inflammatory bowel diseases (IBDs) that are attributed to dysregulated interactions between the gut microbiome and the intestinal mucosa-associated immune system. There are limited studies investigating the role of either IL-1α or IL...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Menghini, Paola, Corridoni, Daniele, Buttó, Ludovica F., Osme, Abdullah, Shivaswamy, Sushma, Lam, Minh, Bamias, Giorgos, Pizarro, Theresa T., Rodriguez-Palacios, Alexander, Dinarello, Charles A., Cominelli, Fabio
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2019
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936591/
https://ncbi.nlm.nih.gov/pubmed/31843928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915043116
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