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Intestinal-Specific TNFα Overexpression Induces Crohn’s-Like Ileitis in Mice
BACKGROUND AND AIM: Human and animal studies have clearly established tumor necrosis factor (TNF)α as an important mediator of Crohn’s disease pathogenesis. However, whether systemic or only local TNFα overproduction is required for the development of chronic intestinal inflammation and Crohn’s dise...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3748077/ https://ncbi.nlm.nih.gov/pubmed/23977323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072594 |
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