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Intestinal-Specific TNFα Overexpression Induces Crohn’s-Like Ileitis in Mice

BACKGROUND AND AIM: Human and animal studies have clearly established tumor necrosis factor (TNF)α as an important mediator of Crohn’s disease pathogenesis. However, whether systemic or only local TNFα overproduction is required for the development of chronic intestinal inflammation and Crohn’s dise...

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Bibliografski detalji
Glavni autori: Bamias, Giorgos, Dahman, Mohamed I., Arseneau, Kristen O., Guanzon, Mitchell, Gruska, Dennis, Pizarro, Theresa T., Cominelli, Fabio
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748077/
https://ncbi.nlm.nih.gov/pubmed/23977323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072594
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