Neutralization of IL-1α ameliorates Crohn’s disease-like ileitis by functional alterations of the gut microbiome

Crohn’s disease and ulcerative colitis are chronic and progressive inflammatory bowel diseases (IBDs) that are attributed to dysregulated interactions between the gut microbiome and the intestinal mucosa-associated immune system. There are limited studies investigating the role of either IL-1α or IL...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Menghini, Paola, Corridoni, Daniele, Buttó, Ludovica F., Osme, Abdullah, Shivaswamy, Sushma, Lam, Minh, Bamias, Giorgos, Pizarro, Theresa T., Rodriguez-Palacios, Alexander, Dinarello, Charles A., Cominelli, Fabio
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936591/
https://ncbi.nlm.nih.gov/pubmed/31843928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915043116
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