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Lewis Acid Catalyzed Enantioselective Photochemical Rearrangements on the Singlet Potential Energy Surface

[Image: see text] The oxadi-π-methane rearrangement of 2,4-cyclohexadienones to bicyclic ketones was found to proceed with high enantioselectivity (92–97% ee) in the presence of catalytic amounts of a chiral Lewis acid (15 examples, 52–80% yield). A notable feature of the transformation is the fact...

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發表在:J Am Chem Soc
Main Authors: Leverenz, Malte, Merten, Christian, Dreuw, Andreas, Bach, Thorsten
格式: Artigo
語言:Inglês
出版: American Chemical Society 2019
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935867/
https://ncbi.nlm.nih.gov/pubmed/31814393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b12068
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