LCAT protects against Lipoprotein‐X formation in a murine model of drug‐induced intrahepatic cholestasis

Familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is a rare genetic disease characterized by low HDL‐C levels, low plasma cholesterol esterification, and the formation of Lipoprotein‐X (Lp‐X), an abnormal cholesterol‐rich lipoprotein particle. LCAT deficiency causes corneal opaci...

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Detalles Bibliográficos
Publicado en:Pharmacol Res Perspect
Main Authors: Amar, Marcelo J. A., Freeman, Lita A., Nishida, Takafumi, Sampson, Maureen L., Pryor, Milton, Vaisman, Boris L., Neufeld, Edward B., Karathanasis, Sotirios K., Remaley, Alan T.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935572/
https://ncbi.nlm.nih.gov/pubmed/31893124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.554
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