Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice

LCAT, a plasma enzyme that esterifies cholesterol, has been proposed to play an antiatherogenic role, but animal and epidemiologic studies have yielded conflicting results. To gain insight into LCAT and the role of free cholesterol (FC) in atherosclerosis, we examined the effect of LCAT over- and un...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Thacker, Seth G., Rousset, Xavier, Esmail, Safiya, Zarzour, Abdalrahman, Jin, Xueting, Collins, Heidi L., Sampson, Maureen, Stonik, John, Demosky, Stephen, Malide, Daniela A., Freeman, Lita, Vaisman, Boris L., Kruth, Howard S., Adelman, Steven J., Remaley, Alan T.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479333/
https://ncbi.nlm.nih.gov/pubmed/25964513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M048629
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