Lipoprotein X Causes Renal Disease in LCAT Deficiency

Human familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is characterized by low HDL, accumulation of an abnormal cholesterol-rich multilamellar particle called lipoprotein-X (LpX) in plasma, and renal disease. The aim of our study was to determine if LpX is nephrotoxic and to gai...

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Pubblicato in:PLoS One
Autori principali: Ossoli, Alice, Neufeld, Edward B., Thacker, Seth G., Vaisman, Boris, Pryor, Milton, Freeman, Lita A., Brantner, Christine A., Baranova, Irina, Francone, Nicolás O., Demosky, Stephen J., Vitali, Cecilia, Locatelli, Monica, Abbate, Mauro, Zoja, Carlamaria, Franceschini, Guido, Calabresi, Laura, Remaley, Alan T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769176/
https://ncbi.nlm.nih.gov/pubmed/26919698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150083
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