Lipoprotein X Causes Renal Disease in LCAT Deficiency

Human familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is characterized by low HDL, accumulation of an abnormal cholesterol-rich multilamellar particle called lipoprotein-X (LpX) in plasma, and renal disease. The aim of our study was to determine if LpX is nephrotoxic and to gai...

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Publicat a:PLoS One
Autors principals: Ossoli, Alice, Neufeld, Edward B., Thacker, Seth G., Vaisman, Boris, Pryor, Milton, Freeman, Lita A., Brantner, Christine A., Baranova, Irina, Francone, Nicolás O., Demosky, Stephen J., Vitali, Cecilia, Locatelli, Monica, Abbate, Mauro, Zoja, Carlamaria, Franceschini, Guido, Calabresi, Laura, Remaley, Alan T.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769176/
https://ncbi.nlm.nih.gov/pubmed/26919698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150083
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