Screening for efficacious anticonvulsants and neuroprotectants in delayed treatment models of organophosphate-induced status epilepticus

Organophosphorus (OP) compounds are deadly chemicals that exert their intoxicating effects through the irreversible inhibition of acetylcholinesterase (AChE). In addition to an excess of peripheral ailments, OP intoxication induces status epilepticus (SE) which if left untreated may lead to permanen...

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Veröffentlicht in:Neuroscience
Hauptverfasser: Barker, Bryan S., Spampanato, Jay, McCarren, Hilary S., Smolik, Melissa, Jackson, Cecelia E., Hornung, Eden N., Yeung, David T., Dudek, F. Edward, McDonough, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935402/
https://ncbi.nlm.nih.gov/pubmed/31783100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.11.020
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