Hydrodynamic stress stimulates growth of cell clusters via the ANXA1/PI3K/AKT axis in colorectal cancer

Cancer cells are exposed to various stresses in vivo, including hydrodynamic stress (HDS). HDS on cancer cells in the blood stream can influence the metastatic potential. Recent studies revealed that circulating tumor cell clusters are more responsible for metastasis than circulating single cells. N...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hagihara, Takeshi, Kondo, Jumpei, Endo, Hiroko, Ohue, Masayuki, Sakai, Yoshiharu, Inoue, Masahiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934682/
https://ncbi.nlm.nih.gov/pubmed/31882967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56739-7
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