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Small subset of Wnt‐activated cells is an initiator of regrowth in colorectal cancer organoids after irradiation

Most colorectal cancers (CRCs) are differentiated adenocarcinomas, which maintain expression of both stemness and differentiation markers. This observation suggests that CRC cells could retain a regeneration system of normal cells upon injury. However, the role of stemness in cancer cell regeneratio...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Endo, Hiroko, Kondo, Jumpei, Onuma, Kunishige, Ohue, Masayuki, Inoue, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734167/
https://ncbi.nlm.nih.gov/pubmed/33043499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14683
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