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Small subset of Wnt‐activated cells is an initiator of regrowth in colorectal cancer organoids after irradiation

Most colorectal cancers (CRCs) are differentiated adenocarcinomas, which maintain expression of both stemness and differentiation markers. This observation suggests that CRC cells could retain a regeneration system of normal cells upon injury. However, the role of stemness in cancer cell regeneratio...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Endo, Hiroko, Kondo, Jumpei, Onuma, Kunishige, Ohue, Masayuki, Inoue, Masahiro
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734167/
https://ncbi.nlm.nih.gov/pubmed/33043499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14683
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