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Small subset of Wnt‐activated cells is an initiator of regrowth in colorectal cancer organoids after irradiation

Most colorectal cancers (CRCs) are differentiated adenocarcinomas, which maintain expression of both stemness and differentiation markers. This observation suggests that CRC cells could retain a regeneration system of normal cells upon injury. However, the role of stemness in cancer cell regeneratio...

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Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Endo, Hiroko, Kondo, Jumpei, Onuma, Kunishige, Ohue, Masayuki, Inoue, Masahiro
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734167/
https://ncbi.nlm.nih.gov/pubmed/33043499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14683
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