In vivo and ex vivo cetuximab sensitivity assay using three-dimensional primary culture system to stratify KRAS mutant colorectal cancer

In clinic, cetuximab, an anti-EGFR antibody, improves treatment outcomes in colorectal cancer (CRC). KRAS-mutant CRC is generally resistant to cetuximab, although difference of the sensitivity among KRAS-mutants has not been studied in detail. We previously developed the cancer tissue-originated sph...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tashiro, Takahiro, Okuyama, Hiroaki, Endo, Hiroko, Kawada, Kenji, Ashida, Yasuko, Ohue, Masayuki, Sakai, Yoshiharu, Inoue, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354432/
https://ncbi.nlm.nih.gov/pubmed/28301591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174151
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados