High-dose chemotherapeutics of intravesical chemotherapy rapidly induce mitochondrial dysfunction in bladder cancer-derived spheroids

Non-muscle invasive bladder cancer is treated with intravesical chemotherapy (IVC) after transurethral resection (TUR) to reduce the probability of recurrence. Despite improvement, the recurrence rate remains high. Intravesical chemotherapeutics at high doses are expected to ablate unresected tumors...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Yoshida, Takahiro, Okuyama, Hiroaki, Nakayama, Masashi, Endo, Hiroko, Nonomura, Norio, Nishimura, Kazuo, Inoue, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317779/
https://ncbi.nlm.nih.gov/pubmed/25363302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12567
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