High-dose chemotherapeutics of intravesical chemotherapy rapidly induce mitochondrial dysfunction in bladder cancer-derived spheroids

Non-muscle invasive bladder cancer is treated with intravesical chemotherapy (IVC) after transurethral resection (TUR) to reduce the probability of recurrence. Despite improvement, the recurrence rate remains high. Intravesical chemotherapeutics at high doses are expected to ablate unresected tumors...

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Vydáno v:Cancer Sci
Hlavní autoři: Yoshida, Takahiro, Okuyama, Hiroaki, Nakayama, Masashi, Endo, Hiroko, Nonomura, Norio, Nishimura, Kazuo, Inoue, Masahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317779/
https://ncbi.nlm.nih.gov/pubmed/25363302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12567
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