High-dose chemotherapeutics of intravesical chemotherapy rapidly induce mitochondrial dysfunction in bladder cancer-derived spheroids

Non-muscle invasive bladder cancer is treated with intravesical chemotherapy (IVC) after transurethral resection (TUR) to reduce the probability of recurrence. Despite improvement, the recurrence rate remains high. Intravesical chemotherapeutics at high doses are expected to ablate unresected tumors...

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Publicat a:Cancer Sci
Autors principals: Yoshida, Takahiro, Okuyama, Hiroaki, Nakayama, Masashi, Endo, Hiroko, Nonomura, Norio, Nishimura, Kazuo, Inoue, Masahiro
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317779/
https://ncbi.nlm.nih.gov/pubmed/25363302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12567
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