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mTORC1 and mTORC2 Differentially Regulate Cell Fate Programs to Coordinate Osteoblastic Differentiation in Mesenchymal Stromal Cells

Vascular regeneration depends on intact function of progenitors of vascular smooth muscle cells such as pericytes and their circulating counterparts, mesenchymal stromal cells (MSC). Deregulated MSC differentiation and maladaptive cell fate programs associated with age and metabolic diseases may exa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Schaub, Theres, Gürgen, Dennis, Maus, Deborah, Lange, Claudia, Tarabykin, Victor, Dragun, Duska, Hegner, Björn
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934532/
https://ncbi.nlm.nih.gov/pubmed/31882658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56237-w
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