An engineered ultra‐high affinity Fab‐Protein G pair enables a modular antibody platform with multifunctional capability

Engineered recombinant antibody‐based reagents are rapidly supplanting traditionally derived antibodies in many cell biological applications. A particularly powerful aspect of these engineered reagents is that other modules having myriad functions can be attached to them either chemically or through...

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Udgivet i:Protein Sci
Main Authors: Slezak, Tomasz, Bailey, Lucas J., Jaskolowski, Mateusz, Nahotko, Dominik A., Filippova, Ekaterina V., Davydova, Elena K., Kossiakoff, Anthony A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Tools for Protein Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933859/
https://ncbi.nlm.nih.gov/pubmed/31622515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3751
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