Inhibition of cyclin‐dependent kinase 7 down‐regulates yes‐associated protein expression in mesothelioma cells

Cyclin‐dependent kinase 7 (CDK7) is a protein kinase that plays a major role in transcription initiation. Yes‐associated protein (YAP) is a main effector of the Hippo/YAP signalling pathway. Here, we investigated the role of CDK7 on YAP regulation in human malignant pleural mesothelioma (MPM). We fo...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Miao, Jinbai, Kyoyama, Hiroyuki, Liu, Luwei, Chan, Geraldine, Wang, Yucheng, Urisman, Anatoly, Yang, Yi‐Lin, Liu, Shu, Xu, Zhidong, Bin, Hu, Li, Hui, Jablons, David M., You, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933402/
https://ncbi.nlm.nih.gov/pubmed/31755214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14841
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