Cucurbitacin E inhibits the Yes-associated protein signaling pathway and suppresses brain metastasis of human non-small cell lung cancer in a murine model

Human non-small cell lung cancer (NSCLC) is associated with an extremely poor prognosis especially for the 40% of patients who develop brain metastasis, and few treatment strategies exist. Cucurbitacin E (CuE), an oxygenated tetracyclic triterpenoid isolated from plants particularly of the family Cu...

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Vydáno v:Oncol Rep
Hlavní autoři: Hsu, Ping-Chih, Tian, Bo, Yang, Yi-Lin, Wang, Yu-Cheng, Liu, Shu, Urisman, Anatoly, Yang, Cheng-Ta, Xu, Zhidong, Jablons, David M., You, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610039/
https://ncbi.nlm.nih.gov/pubmed/31233205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7207
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