Inhibition of yes‐associated protein down‐regulates PD‐L1 (CD274) expression in human malignant pleural mesothelioma

Although tumour PD‐L1 (CD274) expression had been used as a predictive biomarker in checkpoint immunotherapy targeting the PD1/PD‐L1 axis in various cancers, the regulation of PD‐L1 (CD274) expression is unclear. Yes‐associated protein (YAP), an important oncogenic protein in Hippo signalling pathwa...

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Udgivet i:J Cell Mol Med
Main Authors: Hsu, Ping‐Chih, Miao, Jinbai, Wang, Yu‐Cheng, Zhang, Wen‐Qian, Yang, Yi‐Lin, Wang, Chih‐Wei, Yang, Cheng‐Ta, Huang, Zhen, You, Joanna, Xu, Zhidong, Jablons, David M., You, Liang
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980156/
https://ncbi.nlm.nih.gov/pubmed/29575535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13593
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