The Role of Yes-Associated Protein (YAP) in Regulating Programmed Death-Ligand 1 (PD-L1) in Thoracic Cancer

The programmed death-ligand 1(PD-L1)/PD-1 pathway is an immunological checkpoint in cancer cells. The binding of PD-L1 and PD-1 promotes T-cell tolerance and helps tumor cells escape from host immunity. Immunotherapy targeting the PD-L1/PD-1 axis has been developed as an anti-cancer therapy and used...

Full description

Saved in:
Bibliographic Details
Published in:Biomedicines
Main Authors: Hsu, Ping-Chih, Yang, Cheng-Ta, Jablons, David M., You, Liang
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315659/
https://ncbi.nlm.nih.gov/pubmed/30544524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines6040114
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items