CK2α, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells

BACKGROUND: The Hedgehog (Hh) signaling pathway has been implicated in stem cell maintenance and its activation is aberrant in several types of cancer including mesothelioma. Protein kinase CK2 affects several cell signaling pathways through the mechanism of phosphorylation. METHODS: Protein and mRN...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Zhang, Shulin, Yang, Yi-Lin, Wang, Yucheng, You, Bin, Dai, Yuyuan, Chan, Geraldine, Hsieh, David, Kim, Il-Jin, Fang, Li Tai, Au, Alfred, Stoppler, Hubert J, Xu, Zhidong, Jablons, David M, You, Liang
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254219/
https://ncbi.nlm.nih.gov/pubmed/25422081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0093-6
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