CK2α, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells

BACKGROUND: The Hedgehog (Hh) signaling pathway has been implicated in stem cell maintenance and its activation is aberrant in several types of cancer including mesothelioma. Protein kinase CK2 affects several cell signaling pathways through the mechanism of phosphorylation. METHODS: Protein and mRN...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Zhang, Shulin, Yang, Yi-Lin, Wang, Yucheng, You, Bin, Dai, Yuyuan, Chan, Geraldine, Hsieh, David, Kim, Il-Jin, Fang, Li Tai, Au, Alfred, Stoppler, Hubert J, Xu, Zhidong, Jablons, David M, You, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254219/
https://ncbi.nlm.nih.gov/pubmed/25422081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0093-6
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