CK2α, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells

BACKGROUND: The Hedgehog (Hh) signaling pathway has been implicated in stem cell maintenance and its activation is aberrant in several types of cancer including mesothelioma. Protein kinase CK2 affects several cell signaling pathways through the mechanism of phosphorylation. METHODS: Protein and mRN...

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Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Main Authors: Zhang, Shulin, Yang, Yi-Lin, Wang, Yucheng, You, Bin, Dai, Yuyuan, Chan, Geraldine, Hsieh, David, Kim, Il-Jin, Fang, Li Tai, Au, Alfred, Stoppler, Hubert J, Xu, Zhidong, Jablons, David M, You, Liang
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254219/
https://ncbi.nlm.nih.gov/pubmed/25422081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0093-6
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