CK2α, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells

BACKGROUND: The Hedgehog (Hh) signaling pathway has been implicated in stem cell maintenance and its activation is aberrant in several types of cancer including mesothelioma. Protein kinase CK2 affects several cell signaling pathways through the mechanism of phosphorylation. METHODS: Protein and mRN...

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Dades bibliogràfiques
Publicat a:J Exp Clin Cancer Res
Autors principals: Zhang, Shulin, Yang, Yi-Lin, Wang, Yucheng, You, Bin, Dai, Yuyuan, Chan, Geraldine, Hsieh, David, Kim, Il-Jin, Fang, Li Tai, Au, Alfred, Stoppler, Hubert J, Xu, Zhidong, Jablons, David M, You, Liang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254219/
https://ncbi.nlm.nih.gov/pubmed/25422081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0093-6
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