Inhibition of CK2α Down-Regulates Hedgehog/Gli Signaling Leading to a Reduction of a Stem-Like Side Population in Human Lung Cancer Cells

Protein kinase CK2 is frequently elevated in a variety of human cancers. The Hedgehog (Hh) signaling pathway has been implicated in stem cell maintenance, and its aberrant activation has been indicated in several types of cancer, including lung cancer. In this study, we show that CK2 is positively i...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zhang, Shulin, Wang, Yucheng, Mao, Jian-Hua, Hsieh, David, Kim, Il-Jin, Hu, Li-Min, Xu, Zhidong, Long, Hao, Jablons, David M., You, Liang
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2012
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387212/
https://ncbi.nlm.nih.gov/pubmed/22768056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038996
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة