Inhibition of CK2α down-regulates Notch1 signalling in lung cancer cells

Protein kinase CK2 is frequently elevated in a variety of human cancers. The Notch1 signalling pathway has been implicated in stem cell maintenance and its aberrant activation has been shown in several types of cancer including lung cancer. Here, we show, for the first time, that CK2α is a positive...

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Detalhes bibliográficos
Main Authors: Zhang, Shulin, Long, Hao, Yang, Yi-Lin, Wang, Yucheng, Hsieh, David, Li, Weiming, Au, Alfred, Stoppler, Hubert J, Xu, Zhidong, Jablons, David M, You, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729857/
https://ncbi.nlm.nih.gov/pubmed/23651443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12068
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