Dual regulation of microglia and neurons by Astragaloside IV‐mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury

Inflammation and neuronal apoptosis contribute to the progression of secondary injury after spinal cord injury (SCI) and are targets for SCI therapy; autophagy is reported to suppress apoptosis in neuronal cells and M2 polarization may attenuate inflammatory response in microglia, while both are neg...

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Pubblicato in:J Cell Mol Med
Autori principali: Lin, Jialiang, Pan, Xiangxiang, Huang, Chongan, Gu, Mingbao, Chen, Ximiao, Zheng, Xuanqi, Shao, Zhenxuan, Hu, Sunli, Wang, Ben, Lin, Hao, Wu, Yaosen, Tian, Naifeng, Wu, Yan, Gao, Weiyang, Zhou, Yifei, Zhang, Xiaolei, Wang, Xiangyang
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933381/
https://ncbi.nlm.nih.gov/pubmed/31675186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14776
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