Dual regulation of microglia and neurons by Astragaloside IV‐mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury

Inflammation and neuronal apoptosis contribute to the progression of secondary injury after spinal cord injury (SCI) and are targets for SCI therapy; autophagy is reported to suppress apoptosis in neuronal cells and M2 polarization may attenuate inflammatory response in microglia, while both are neg...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Lin, Jialiang, Pan, Xiangxiang, Huang, Chongan, Gu, Mingbao, Chen, Ximiao, Zheng, Xuanqi, Shao, Zhenxuan, Hu, Sunli, Wang, Ben, Lin, Hao, Wu, Yaosen, Tian, Naifeng, Wu, Yan, Gao, Weiyang, Zhou, Yifei, Zhang, Xiaolei, Wang, Xiangyang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933381/
https://ncbi.nlm.nih.gov/pubmed/31675186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14776
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