Catalpol alleviates adriamycin‐induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro

BACKGROUND AND PURPOSE: Catalpol, a water‐soluble active ingredient isolated from Rehmannia glutinosa, exhibits multiple pharmacological activities. However, the mechanism(s) underlying protection against renal injury by catalpol remains unknown. EXPERIMENTAL APPROACH: Adriamycin‐induced kidney inju...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Zhang, Jiangnan, Bi, Ran, Meng, Qiang, Wang, Changyuan, Huo, Xiaokui, Liu, Zhihao, Wang, Chong, Sun, Pengyuan, Sun, Huijun, Ma, Xiaodong, Wu, Jingjing, Liu, Kexin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932948/
https://ncbi.nlm.nih.gov/pubmed/31378931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14822
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