Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains

Alterations of the PALB2 tumor suppressor gene have been identified in familial breast, ovarian and pancreatic cancer cases. PALB2 cooperates with BRCA1/2 proteins through physical interaction in initiation of homologous recombination, in maintenance of genome integrity following DNA double-strand b...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Park, Dongju, Shakya, Reena, Koivisto, Christopher, Pitarresi, Jason R., Szabolcs, Matthias, Kladney, Raleigh, Hadjis, Ashley, Mace, Thomas A., Ludwig, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932818/
https://ncbi.nlm.nih.gov/pubmed/31877165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226714
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