Erastin Reverses ABCB1-Mediated Docetaxel Resistance in Ovarian Cancer

Overexpression of drug efflux transport ABCB1 is correlated with multidrug resistance (MDR) among cancer cells. Upregulation of ABCB1 accounts for the recurrence of resistance to docetaxel therapy in ovarian cancer with poor survival. Erastin is a novel and specific small molecule that targets SLC7A...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Oncol
Päätekijät: Zhou, Hai-Hong, Chen, Xu, Cai, Lu-Ya, Nan, Xing-Wei, Chen, Jia-Hua, Chen, Xiu-Xiu, Yang, Yang, Xing, Zi-Hao, Wei, Meng-Ning, Li, Yao, Wang, Sheng-Te, Liu, Kun, Shi, Zhi, Yan, Xiao-Jian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019
Aiheet:
Oncology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930896/
https://ncbi.nlm.nih.gov/pubmed/31921655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01398
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