Midostaurin Reverses ABCB1-Mediated Multidrug Resistance, an in vitro Study

Overexpression of ABC transporters in cancer cells is an underlying mechanism of multidrug resistance (MDR), leading to insensitive response to chemotherapeutic strategies. Thus, MDR is often results in treatment failure in the clinic. In this study, we found midostaurin, a Food and Drug Administrat...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Ji, Ning, Yang, Yuqi, Cai, Chao-Yun, Wang, Jing-Quan, Lei, Zi-Ning, Wu, Zhuo-Xun, Cui, Qingbin, Yang, Dong-Hua, Chen, Zhe-Sheng, Kong, Dexin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591272/
https://ncbi.nlm.nih.gov/pubmed/31275850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00514
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