Midostaurin Reverses ABCB1-Mediated Multidrug Resistance, an in vitro Study

Overexpression of ABC transporters in cancer cells is an underlying mechanism of multidrug resistance (MDR), leading to insensitive response to chemotherapeutic strategies. Thus, MDR is often results in treatment failure in the clinic. In this study, we found midostaurin, a Food and Drug Administrat...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Ji, Ning, Yang, Yuqi, Cai, Chao-Yun, Wang, Jing-Quan, Lei, Zi-Ning, Wu, Zhuo-Xun, Cui, Qingbin, Yang, Dong-Hua, Chen, Zhe-Sheng, Kong, Dexin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591272/
https://ncbi.nlm.nih.gov/pubmed/31275850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00514
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