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Novel Convenient Approach to the Solid-Phase Synthesis of Oligonucleotide Conjugates
A novel and convenient approach for the solid-phase 5′-functionalization of oligonucleotides is proposed in this article. The approach is based on the activation of free 5′-hydroxyl of polymer support-bound protected oligonucleotides by N,N′-disuccinimidyl carbonate followed by interaction with amin...
Gardado en:
| Publicado en: | Molecules |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6930482/ https://ncbi.nlm.nih.gov/pubmed/31771111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24234266 |
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