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A Versatile Solid-Phase Approach to the Synthesis of Oligonucleotide Conjugates with Biodegradable Hydrazone Linker

One of the ways to efficiently deliver various drugs, including therapeutic nucleic acids, into the cells is conjugating them with different transport ligands via labile or stable bonds. A convenient solid-phase approach for the synthesis of 5′-conjugates of oligonucleotides with biodegradable pH-se...

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Vydáno v:Molecules
Hlavní autoři: Meschaninova, Mariya I., Entelis, Nina S., Chernolovskaya, Elena L., Venyaminova, Alya G.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067880/
https://ncbi.nlm.nih.gov/pubmed/33917095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26082119
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