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Solid Phase Synthesis of a Metronidazole Oligonucleotide Conjugate
Direct, solid phase synthesis of an oligonucleotide conjugate of the antibiotic drug metronidazole was accomplished by the phosphoramidite method. Removal of protecting groups and cleavage from the controlled pore glass (CPG) solid support was successful using mild conditions (20% Et(3)N in pyridine...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6148672/ https://ncbi.nlm.nih.gov/pubmed/17962782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/11060486 |
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