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Solid Phase Synthesis of a Metronidazole Oligonucleotide Conjugate

Direct, solid phase synthesis of an oligonucleotide conjugate of the antibiotic drug metronidazole was accomplished by the phosphoramidite method. Removal of protecting groups and cleavage from the controlled pore glass (CPG) solid support was successful using mild conditions (20% Et(3)N in pyridine...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Walsh, Andrew J., Davis, Michael L., Fraser, William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148672/
https://ncbi.nlm.nih.gov/pubmed/17962782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/11060486
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